From Data to Models
New Bioinformatics Methods and Tools for Data-Driven, Predictive Dynamic Modelling in Biotechnological Applications

2014 The Systems Biology Modelling Cycle EBI workshop (supported by BioPreDyn)

2014 The Systems Biology Modelling Cycle EBI workshop (supported by BioPreDyn)

This course will provide a detailed overview of state-of-the-art modelling methods and tools in computational systems biology, focusing especially on dynamic (mechanistic) models.

Registration at the EBI site required. Course fee: £600.00 (includes course, computer use, accomadation). Travel bursaries available.

We will combine lectures on modelling approaches, computer-based practicals, and organized discussions, to identify the key challenges, opportunities, and bottlenecks in the field.

The workshop is aimed at advanced PhD students, post-doctoral, and more senior researchers who are using (or planning to use) systems-based dynamic modelling approaches to understand biological problems.

During this course you will learn about:


    Databases and web services for dynamic modelling: BioModels, Bioservices

  • Visualisation tools: GPy

  • Tools for dynamic modelling: CellNOpt, COPASI, Meigo, AMIGO

After this course you should be able to:

  • Browse and access public databases for dynamic modeling

  • Use tools to visualize and analyze biological time-series data

  • Comprehend the key concepts of network inference methods, dynamic modelling (including parameter estimation, optimal design of experiments, and uncertainty quantification and model selection), reverse engineering of gene regulatory networks, and computational metabolic engineering

  • Discuss some applications of kinetic models to biotechnological processes involving microorganisms (E. coli, S. cerevisiae) and CHO cells

  • Apply the systems biology modelling cycle and related computational workflows to biological problems































May 12 to May 15
EMBL-European Bioinformatics Institute
Cambridgeshire CB10 1SD
United Kingdom