Our group has long-standing experience in high-performance computing, scientific visuali- sation, modelling and simulation in computational biology, bio-medical applications and physics. Within computational biology we do research at a range of different levels of organisation (genome-gene regulatory networks-cells-tissue-organism). We work on modelling and analysis of gene regulation in cnidarians (corals and Nematostella vectensis), sponges, yeast and Drosophila. We do research on bio-mineralisation in corals and sponges (experimental and modelling work). We are working on growth and form of corals and the influence of light and hydrodynamics on the morphological plasticity and calcification in basal organisms (sponges and corals). This work is a combination of modelling work, a genetic comparison between different growth forms, phylogenetics, morphometrics of three- dimensional growth forms obtained from CT scans and experimental work.